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Three-year efficacy and safety of exenatide once weekly: a pooled analysis of three trials
United States: Robert Busch
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In the Phase 3 ESSENCE trial for metabolic dysfunction-associated steatohepatitis (MASH), semaglutide 2.4 mg weekly produced a 28.7 percentage-point difference over placebo in MASH resolution without fibrosis worsening, and a 14.4 percentage-point difference over placebo in fibrosis improvement without MASH worsening with 32.7% of semaglutide-treated patients achieving both endpoints simultaneously
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